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Ivan the terrible

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Posts posted by Ivan the terrible

  1. 3 hours ago, lazarus said:

    The hits just keep on coming...

    Growing Body Of Evidence Suggests Masks Protect Those Wearing Them, Too

    Podcast: https://www.npr.org/2020/07/20/893227088/growing-body-of-evidence-suggests-masks-protect-those-wearing-them-too?fbclid=IwAR2FOu7w5Mu-Bf6p-4UQqCtMw28wg-xrmtqUolcHd_jw6BgIIJZRkF8xMGk

    AILSA CHANG, HOST:

    As we just heard, even though most face masks make lip reading harder or cover a smile, we've been told again and again to wear them because wearing a mask lowers the chances that you will spread COVID-19 to others. But a growing body of evidence suggests that the opposite is also true. That is wearing a mask might protect you, too. Here to walk us through the research is Dr. Monica Gandhi, an infectious disease specialist at the University of California, San Francisco.

    Welcome.

    MONICA GANDHI: Thank you very much for having me.

    CHANG: All right. So briefly walk us through the theory here. How are masks also beneficial for the people wearing them?

    GANDHI: Right. So as you said, they're very beneficial to protect others because you shed at high rates from your nose and mouth even when you feel fine. So that had been kind of the party line for a while. But they really are protective of you as an individual. And sort of putting it all together, it really is that the less virus that you get in, the less sick you're likely to be. So not only do masks protect you - and we've seen from getting the virus and altogether. And that's been seen in hamster studies. That's been seen in a health care worker study that was just published last week in JAMA. But if you do get the virus in, you get very little in. And you're likely to get what's called an asymptomatic infection or not have any symptoms at all and - or a very mild infection. So it really is based on the fact that we've known for many years now - probably a hundred - that the more virus you get into your system, the more likely you are to get sick. And these masks protect you.

    CHANG: Oh, that's so interesting. So if mask wearing does turn out to lower the severity of the disease because you're lowering the amount of virus that you're taking in, would that translate then to fewer deaths?

    GANDHI: Yes. So it really looks like any country that has adopted universal mask wearing - and many, many countries have - even as they open up and they're seeing each other more and there's more cases, it has led to much, much fewer deaths or severe illness. So the idea about this virus is it's completely bizarre how it can cause no symptoms in some people and very, very severe symptoms in others.

    CHANG: Yeah.

    GANDHI: And what we want to do by wearing a mask is get down the bad stuff about this virus that it can cause very severe illness. And, yes, we've absolutely not only seen that in countries but even in settings where there are outbreaks but everyone masked, there's, like, a 95% rate of not having symptoms at all. There was actually a outbreak in a chicken factory, outbreak in a seafood factory in this country. But everyone was masking. And it was 95% asymptomatic rate of infection.

    CHANG: Oh, that is fascinating. I mean, mask wearing has become divisive, right? It's a political issue in many parts of the country. Do you think this evidence could help change the public-health messaging around masks by appealing to people's self-interest?

    GANDHI: Yes. I think that I - what I'm hoping for is that I do understand that politics always gets into everything. This will protect you, your family as well as others. This will protect you. That means that we should all be wearing a mask because we need to get through this pandemic. We are miserable. This is taking a long time. And if we...

    CHANG: Right.

    GANDHI: ...All put this over our faces, we will get through it faster.

    CHANG: All right. That is Dr. Monica Gandhi. She is a professor of medicine and the director of the UCSF Center for AIDS Research.

    Thank you.

    GANDHI: Thank you.

    rolleyes ...its not new ..studies with flu within a household shows masks reduce transmission rates by 75% years ago !!

    It was politically expedient to say there were not necessary(they didnt have enough),then a forgetful lapse(they didnt have enough ),now they have the evidence lol

    Face coverings(not masks) are pretty much useless ...I wouldnt bother..they get so wet from exhaled breath (H20) the material becomes super porous  

  2. On 7/22/2020 at 1:09 AM, Krapow said:

    Aye, you'd wonder at that wouldn't you.

    Thailand, Vietnam, South Korea etc, places like that who are good at wearing the masks, understand the benefit of it.

    Them then getting a handle on the virus far, far better than say the likes of the US. 

    Obviously just a coincidence. 

    Uk 4th  after  Belgium ,  San Marino and Andorra  in terms deaths per million population...better analogy would be "the likes of the UK"

    Usa 11th

    https://www.worldometers.info/coronavirus/

  3. 12 minutes ago, Krapow said:

    Boris reckons football fans can go back to the games by October, and mostly everything back to normal by Christmas. 

    🤣

    in the abscence of a vaccine...no bloody way,,,1 person from melbourne has just infected 34 people in NSW some directly ,some via a second party...a superspreader...huge viral load  apparently in his swabs..to spread to others while he was feeling relatively ok...a truckie apparently

    this thing is so bloody infectious to other people.  its rabidly promiscous ..hence masks ,hand washing and social distancing are absolutely required

  4. 3 minutes ago, fygjam said:

    Speak for yourself sunburnt one.

    Genetic data on half a million Brits reveal ongoing evolution and Neanderthal legacy

    They found Neanderthal variants that boost the odds that a person smokes, is an evening person rather than a morning person, and is prone to sunburn and depression.

     

    I tick the boxes...lots of us in business ..like most  successful genes ,their survival confers an evolutionary advantage which we currently dont readily understand.

    The "selfish gene"

  5. 29 minutes ago, Nightcrawler said:

    Not all of us, but your future not looking great 😀😀😀

    https://youtu.be/0e0qYP_PTlY

    Ha Ha ..ancient spoken  wisdom then  embedded in our  ancient literature of discerning right from wrong ,good from bad then translated into  the majesty of English Common Law ,through which the Western Hemisphere Civilisations made leaps so great in their knowledge  that led us into the Enlightenment and all the great stuff that you have today..like nasal/ear  hair removers and  online BBC 🤣 

  6. 18 hours ago, Evil Penevil said:

    Considering the high prevalence of Neanderthal DNA in males visiting Pattaya, this article could be of relevance.  My bold highlights.  I wonder what the risk is for males with troll or hobbit DNA?

    Evil

    BGR.JPG.90ed795c30f10c8d04bc8ac4ab0c69e6.JPG

    Neanderthal DNA might be a risk factor 
    for severe coronavirus cases

    July 14th, 2020 at 10:12 PM
    • Several risk factors have been associated with severe coronavirus illness, and health officials have a good idea about which patients are likely to develop symptoms and complications after infection.
    • It’s still unclear why the coronavirus affects some people more severely than others, and why many people deal with mild to moderate cases of COVID-19.
    • A new study that’s yet to be peer-reviewed says that a segment containing genes inherited from Neanderthals 60,000 years ago can be associated with an increased risk of severe COVID-19 cases.

    Not all of the people who test positive for the novel coronavirus will experience a bad case of COVID-19 requiring oxygen therapy or mechanical ventilation. That’s something many people will say in order to minimize the ongoing surge in cases. That is somewhat true. Some will not realize they carry the disease, and others will experience a milder version of COVID-19. A wide variety of patients are at risk of developing severe illnesses, but that doesn’t guarantee that everyone else will survive. Once you start showing symptoms, there’s no telling which way the disease will go, even if you don’t have any medical conditions that can complicate the disease.

    Doctors are still trying to understand why COVID-19 is a more significant threat to old people suffering from certain preexisting conditions and why men are more likely to die than women of the same age. And physicians have discovered therapies that can lower the COVID-19 death rate for patients who do go on ventilators, but the fatality percentage remains high. Amid the ongoing coronavirus research, genetics stand out.

    The science can keep track of coronavirus mutation, but also try to explain the risk factors at the gene level for severe COVID-19 cases. A new paper did just that, and the conclusion is incredible: It’s the Neanderthal in you that could be responsible for an increased risk of developing a severe case of coronavirus.

    (READ MORE)

    we're doomed on this forum

  7. 22 minutes ago, Evil Penevil said:

    News17.JPG

    Who is most likely to die from COVID-19?

    by: Judith Retana

    Posted:  / Updated: 

    RALEIGH, N.C. (WNCN)- The Centers for Disease Control painted a grim picture of characteristics in persons who have died from COVID-19.

    An analysis by CBS17.com found white men, over age 65 with cardiovascular disease were most likely to die from COVID-19.

    Underlying health conditions were a considerable factor in severe illness and deaths associated with COVID-19. In three-quarters of deaths, there was at least one underlying health condition present. In about half the deaths, there were at least two underlying health conditions.

    Cardiovascular disease was the most prominent.

    Underlying Condition Percentage of deaths present
    Cardiovascular disease 61%
    Diabetes 40%
    Chronic kidney disease 21%
    Chronic lung disease 19%
    Immunosuppression 16%
    Source: CDC

    Nationally, while 35 percent of deaths were in Whites, second place was fairly close between Blacks (24.9 percent) and Hispanics (24.4 percent).

    Men made up 60 percent of all cases nationwide.

    The increased risk is partly due to the way COVID-19 impacts the body.

    “Patients who have COVID-19 are at increased risk for blood clots that can form in various blood vessels. This can lead to heart attack or even what we call a pulmonary embolism,’ said Dr. Sunil Rao, a cardiologist at Duke University School of Medicine

    It is important to note, the CDC’s report is based on information compiled from February 12–May 18, 2020.

    Dr. Rao said he was not surprised by the makeup of the majority of deaths. He said cardiovascular disease is a very common disease affecting older people.

    What was more concerning to him was the CDC’s report that younger Black and LatinX patients were also dying from COVID-19.

    “That’s quite surprising because we had originally thought that younger patients were being protected from severe COVID-19 infection. We now know that’s not the case. In fact, the CDC has done away with an age threshold. The older you are, the more at risk you are. It’s a continuous risk. Patients who are in the Black and Latino or Hispanic community, those patients seem to be at even higher risk for the severe COVID-19 infection at younger ages than their white counterparts,” said Dr. Rao.

    The report found “Overall, 34.9 percent of Hispanic and 29.5 percent of nonwhite decedents were aged under 65 years, compared with 13.2 percent of white, non-Hispanic decedents.”

     

    Read the entire report here.

    As I said further up the thread this is a metabolic disease primarily wrt mortality,obesity(metabolic syndrome)u ,cv disease,diabetes,kidney disease etc...medcram covers this brilliantly btw...its easy to digest.. I would strongly  recommend the medcram site

  8. 3 hours ago, Painter said:

    Hang on....

    Edit...

    Oxford scientists believe they have made a breakthrough in their quest for a Covid-19 vaccine after discovering that the jab triggers a response that may offer a "double defence" against the virus.

    Phase I human trials of the world-leading Oxford vaccine have shown that it generates an immune response against the disease, the Telegraph has learned.

    Blood samples taken from a group of UK volunteers given a dose of the vaccine showed that it stimulated the body to produce both antibodies and "killer T-cells", a senior source said.

    The discovery is promising because separate studies have suggested that antibodies may fade away within months while T-cells can stay in circulation for years.

    However the source cautioned that the results, while “extremely promising”, did not yet prove that the Oxford vaccine provides long-lasting immunity against Covid-19.

    “I can tell you that we now know the Oxford vaccine covers both bases - it produces both a T cell and an antibody response,” the senior source told the Telegraph.

    “It’s the combination of these two that will hopefully keep people safe.

    “So far, so good. It’s an important moment. But we still have a long way to go.”

    Another source close to the team described the presence of both antibodies and T-cells as a “double defence” against Covid-19.

    The full findings will be published in the Lancet medical journal on July 20, it was confirmed on Wednesday night.

    The findings are based on initial results from a Phase 1 clinical trial, which began in Oxford in April when doses of the vaccine were given to 500 volunteers. A major trial is currently underway involving 5,000 volunteers in virus-hit Brazil to prove the vaccine is effective, while the drugmaker AstraZeneca has signed a deal to produce up to two billion doses. If all goes well, the researchers hope the vaccine may be ready as early as October.

    Speaking on Peston on ITV on Wednesday night, Matt Hancock, the Health Secretary, said the best case scenario is for the vaccine to be available this year, but added it will "more likely" be ready in 2021.

    The initial data also suggests that the ChAdOx1 nCoV-19 vaccine is safe with no major side effects, it is understood, although further work will be needed. The team is also evaluating the level of dose needed to produce an effective response.

    Stocks soared on Wednesday after reports of positive news on the Oxford vaccine to be released next week. Shares in AstraZeneca, the drugmaker licensed to produce billions of doses of the Oxford vaccine, jumped 5.2 per cemt.

    David Carpenter, chair of the Berkshire Research Ethics Committee (REC), which approved the Oxford trial and continues to work with scientists on amendments, told the Telegraph that the team were “absolutely on track”.

    “They can strengthen findings by targeting people in hospitals, healthcare professionals, where the spread is (more) likely to happen.

    “Nobody can put final dates.. things might go wrong but the reality is that by working with a big pharma company, that vaccine could be fairly widely available around September and that is the sort of target they are working on.”

    Antibodies vs T-cells

    Scientists increasingly believe that any successful vaccine may need to trigger both an antibody and T-cell response – the two key aspects of our "adaptive" immune system.

    Antibodies, produced by B cells, recognise a virus circulating in our body and neutralise it, preventing it from entering our cells.

    T-cells are slightly different. They help to make antibodies but also directly attack human cells that have already become infected with a virus. These cells are vital in fighting a number of illnesses, including measles and the common cold.

    When we have fought off an infection once, we retain a number of "memory" cells that are primed and ready to attack if we are infected with the virus again – and it is this process that a vaccine is attempting to replicate.

    "What I would say is that if a vaccine elicits both responses it is potentially going to be better than one that just elicits one arm of the immune system," said Professor Jonathan Ball, a virologist at the University of Nottingham.

    "The best vaccines tend to be those that mimic a viral infection, and this 'natural' infection would trigger both antibodies and T-cells."

    Research published in the last few weeks appears to underline the importance of triggering a broad immune response.

    A team at King's College London has found that antibodies do not remain in our blood for long. Of 96 people tracked, 60 per cent had a "potent" Covid-19 antibody response at the height of their infection.

    This fell to just 17 per cent three months later – in some, antibodies were almost undetectable.

    Separately, studies have detected T-cell reactivity against Sars-CoV-2 in those who have never been exposed to the virus.

    But Professor Beate Kampmann, director of the Vaccine Centre at the London School of Hygiene and Tropical Medicine, warned that this does not mean vaccines which fail to produce T-cells will not be effective.

    Fading antibodies do not necessarily equate to fading immunity – it is entirely possible that antibodies in our blood may fall below detectable levels while still providing an effective defence against reinfection.

    Likewise, just because a candidate elicits a T-cell response, this "does not guarantee that it will be safe and effective".

    "A safe and effective vaccine is not just around the corner, and there are many unknowns – much bigger datasets and trials are needed," warned Prof Kampmann.

     

    very promising indeed

  9. 37 minutes ago, fygjam said:

    Potential COVID-19 vaccine clears 'major milestone': Sask. researchers

    Research centre says candidate vaccine induced a 'strong immune response' in ferrets

     

    Ferrets around the world are ecstatic at the prospect of being able to ditch the macho sapping mask.

     

     

    did you ask the ones in your grundies?

  10. 1 hour ago, Thai Spice said:

    Following the US stock market, and a few bio pharma companies, I know it usually takes years to have a new medication approved for sales by the FDA.

    Trials in several steps, each over long periods  etc...

    And now they will suddenly approve a miracle vaccin in a few months ? 

    And fabricate millions of them....

    Let's be serious ......

    China has started earlier to work on this, they have gigantic technical means, the full government support, much less regulatory restrictions .... and they haven't come out with even a hint of one.

     

     

    not true thet are testing the sino vaccine on their armed forces...they have  a few million of those...i think 2 million was the eventual test group ...but they then have to send them to brazil !

  11. 3 minutes ago, Thai Spice said:

    Another crazy theorie.... 

    A quick google in french (after all the guy is French) will return a dozen of serious newspapers or websites saying his theorie is very doubtfull to put it politely.

    And a search in English will probably return the same. 

     

    he has some serious credentials and,at least,he should be listened to

  12. 33 minutes ago, code_slayer_bkk said:

    Yea .. I was not attacking Boris as a person or as man .... for sure ...

    I was just trying to make a point ... all of this drivel political insinuations gets old really fucking old against Trump ...

    i agree with you entirely Code...Trump virtually alone ,other than Oz and NZ called the border closure(the biggest,only  single source of the virus) right from the outset...its a shame he didnt do it for all countries including the EU  instead of just China from the outset.Remember Bidens response at that time ...called him xenophobic and racist...dopy Joe

    By the time he banned EU  it was already too late

    • Like 1
  13. 2 minutes ago, Mr. Smooth said:

    This is for a country that has had zero cases of Covid in several weeks, am I right? So FFS, just have everyone off the plane stand by for a temperature check and if normal, then have a pleasant stay. If not normal, then please come with us to experience our luxurious accommodations with three squares a day and a couple of tests over the next 14 days.

    Have some hotels on standby and get on with it. Christ.....you would think to get into Thailand, you have to break down Einstein's theory of relativity and give up the nuclear codes.

    And for what? All to be charged 105 baht for a bottle of Chang and watch a flabby dancer do a two step shuffle to a 25 year old Cranberries song?

    the permanent ex pats are lapping this up ,mate...just salivating at your detention

    • Haha 1
  14. 10 minutes ago, fygjam said:

    I suppose you have a signed photo of Pinochet in your wallet.

     

    Why...i value freedom ...is he your arch enemy?...you would be better placed opposing  Lennin,Stalin .Pol pot,chavez,castro.mao..all socialists btw who thought they could usher in the nirvana under their watch...result...100million + dead 

    Will you useful idiots ever learn?

     

    • Like 2
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