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COVID 19 GLOBAL


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33 minutes ago, fygjam said:

You keep saying so, perhaps you'd like to give details.

This from the NHS may help you.

image.png

https://www.england.nhs.uk/coronavirus/secondary-care/management-confirmed-coronavirus-covid-19/clinical-medical-management/

 

Remdisivir works. 

I wouldn't listen to a word the NHS says. It's a basket case healthcare system befitting of a third world nation. 

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6 minutes ago, dcfc2007 said:

Remdisivir works. 

I wouldn't listen to a word the NHS says. It's a basket case healthcare system befitting of a third world nation. 

Really?

https://www.who.int/news-room/feature-stories/detail/who-recommends-against-the-use-of-remdesivir-in-covid-19-patients

WHO has issued a conditional recommendation against the use of remdesivir in hospitalized patients, regardless of disease severity, as there is currently no evidence that remdesivir improves survival and other outcomes in these patients.

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30 minutes ago, dcfc2007 said:

Remdisivir works. 

Got some in your medicine cabinet or first aid kit?

Britain rations remdesivir as COVID-19 hospitalisations rise

In case you weren't aware. Remdesivir is administered via IV in hospital over a 5 day course.

Gilead Sciences’ remdesivir has been shown to shorten hospital recovery time in severe cases of COVID-19, although it has not been shown to reduce mortality.

You get out of hospital a day earlier or you're dead.

 

 

 

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3 hours ago, dcfc2007 said:

A balancing act? 

Are you fucking kidding me? Jo Jo op

What's balanced about it. Most of us a still suffering under an arbitrary lockdown, jobs are being lost, more lives are being lost to other untreated illnesses, and yet again working class people are suffering the most. 

The middle class types can afford to work from home, no skin off their nose, and it isn't these scientists and bureaucrats on six figure salaries trying to come up with excuses to tell their kids why santa Claus is coming this year. 

We have theraputic treatments, we have a vaccine, excess deaths are no great cause for concern. 

Now is the time to get on with life. 

If people like you want to his behind the sofa, fine. But you should not be allowed to hold the rest of society back from functioning. 

"Now" is not quite here yet. It is going to take a while to roll out the vaccines and there will be 2 shots per person with a 21 day interval, then following that, the immunisation is not a full strength for at least another 7 days.  

The reason for a second spike, is because lockdown were eased, and many did not take precautions or just refused to take on their own social responsibility. 

Many, who cannot work from home have been furloughed, but of course many have been affected financially as well as socially. But referring to my comment of a balancing act, it has been a balance between trying to keep infections down, and lockdown measures which still keep essential services going and the general economy. We have all suffered, but the real culprit is the Corona Virus which doesn't care about anything. 

We don't have a fully rolled out or fully tested treatment that will save lives, or reduce hospital admissions for the most vulnerable, yet. Hopefully that will soon come. 

In the meantime, I suspect that the 3 tiers of lockdown will remain  at certain periods up until Spring 2021 or beyond

My feeling is that if we have got through the last 9 months, then another 3 or 4 months of preventative behaviour is not so bad, knowing that there is a light at the end of the tunnel. 

That said, if we can return to near normality, great, but C19 is not just going to pack its bags and leave without a fight and there are still a few unknowns about the vaccine, such as how effective it WILL be in when it's live and how long it will last etc.  Then of course, it will also depend on enough people taking up the vaccine as it is not compulsory and not everyone in the lower tiers of distribution will agree to be vaccinated. 

So it's not over yet, but looking far more promising than it did 6 months ago. But we still don't have a magic wand. 

We All have equal access to Government Sources, Scientific sources, the Mainstream and fringe media. Social Media and Conspiracy theories therewithin. 

In conjunction with our own personal experiences we base our individual opinions on that which we see and read about C19.  Yet those opinions will vary widely. 

That's what happens here when discussing the issue. Who is to say who is right or wrong?  I think the truth is, that none of us really know for sure, and even the Government do not know for sure how all of this is going to pan out over the next 12 months or beyond. 

Viruses have a habit of mutating when under attack. Let's hope not and that scientists can keep on top of it by altering vaccines accordingly. 

The only thing that is in our hands is to act responsibly as individuals for the common good

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3 hours ago, Nightcrawler said:

"Now" is not quite here yet. It is going to take a while to roll out the vaccines and there will be 2 shots per person with a 21 day interval, then following that, the immunisation is not a full strength for at least another 7 days.  

The reason for a second spike, is because lockdown were eased, and many did not take precautions or just refused to take on their own social responsibility. 

Many, who cannot work from home have been furloughed, but of course many have been affected financially as well as socially. But referring to my comment of a balancing act, it has been a balance between trying to keep infections down, and lockdown measures which still keep essential services going and the general economy. We have all suffered, but the real culprit is the Corona Virus which doesn't care about anything. 

We don't have a fully rolled out or fully tested treatment that will save lives, or reduce hospital admissions for the most vulnerable, yet. Hopefully that will soon come. 

In the meantime, I suspect that the 3 tiers of lockdown will remain  at certain periods up until Spring 2021 or beyond

My feeling is that if we have got through the last 9 months, then another 3 or 4 months of preventative behaviour is not so bad, knowing that there is a light at the end of the tunnel. 

That said, if we can return to near normality, great, but C19 is not just going to pack its bags and leave without a fight and there are still a few unknowns about the vaccine, such as how effective it WILL be in when it's live and how long it will last etc.  Then of course, it will also depend on enough people taking up the vaccine as it is not compulsory and not everyone in the lower tiers of distribution will agree to be vaccinated. 

So it's not over yet, but looking far more promising than it did 6 months ago. But we still don't have a magic wand. 

We All have equal access to Government Sources, Scientific sources, the Mainstream and fringe media. Social Media and Conspiracy theories therewithin. 

In conjunction with our own personal experiences we base our individual opinions on that which we see and read about C19.  Yet those opinions will vary widely. 

That's what happens here when discussing the issue. Who is to say who is right or wrong?  I think the truth is, that none of us really know for sure, and even the Government do not know for sure how all of this is going to pan out over the next 12 months or beyond. 

Viruses have a habit of mutating when under attack. Let's hope not and that scientists can keep on top of it by altering vaccines accordingly. 

The only thing that is in our hands is to act responsibly as individuals for the common good

What a load of bollocks. 

🤣🤣🤣🤣

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4 hours ago, fygjam said:

Got some in your medicine cabinet or first aid kit?

Britain rations remdesivir as COVID-19 hospitalisations rise

In case you weren't aware. Remdesivir is administered via IV in hospital over a 5 day course.

Gilead Sciences’ remdesivir has been shown to shorten hospital recovery time in severe cases of COVID-19, although it has not been shown to reduce mortality.

You get out of hospital a day earlier or you're dead.

 

 

 

Why are you sharing Britain and the NHS. The NHS is a crumbling, bureaucratic shitpit full of diversity co-ordinators and some of the worst health outcomes in the developed world. 

 

Researchers have now completed the trial, known as the Adaptive COVID-19 Treatment Trial (ACTT-1). The study was funded by the National Institute of Allergy and Infectious Diseases (NIAID). The final report appeared in the New England Journal of Medicine on October 8, 2020.

Scientists randomly assigned 1,062 hospitalized COVID-19 patients to receive remdesivir or a placebo plus standard treatment. The patients received an intravenous infusion of remdesivir or placebo for up to 10 days.

The final results showed that the antiviral treatment was beneficial, consistent with the preliminary findings. Patients who received remdesivir were quicker to recover, which was defined as being medically stable enough to be discharged from the hospital. The median recovery time was 10 days with remdesivir compared to 15 days for the placebo group. Patients given remdesivir were more likely to have improved by day 15.

Remdesivir also improved mortality rates for those receiving supplemental oxygen (4% with remdesivir versus 13% with placebo at day 29 of treatment). All-cause mortality among all patients was 11% with remdesivir and 15% with placebo at day 29, but this difference between the treatment groups was not large enough to rule out chance. The preliminary findings hadn’t shown an effect on mortality.

The study also suggested that remdesivir treatment may prevent patients from progressing to more severe respiratory disease. Those treated with remdesivir were less likely to need high levels of respiratory support. Remdesivir appeared to most benefit patients who were receiving supplemental oxygen.

“Our findings show that remdesivir is a beneficial treatment for patients with COVID-19,” says study author Dr. John Beigel of NIAID. “It may also help to conserve scarce health care resources, such as ventilators, during this pandemic.”

https://www.nih.gov/news-events/nih-research-matters/final-report-confirms-remdesivir-benefits-covid-19#:~:text=By April%2C early results indicated,people hospitalized with COVID-19.

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The creators of the Sputnik V vaccine have denied that Russians must quit drinking for nearly two months while receiving the jabs.

Scientists attempted to head off a public row over whether millions would have to go teetotal to join the country’s mass vaccination programme. Following a day of heated deliberations, the head of the Gamaleya research centre that developed Sputnik V said that patients should avoid drinking for just six days.

Reuters reports:

Anna Popova, head of the consumer health watchdog, told the Komsomolskaya Pravda radio station on Tuesday that people should stop drinking alcohol at least two weeks before getting the first of two injections. They should continue to abstain for a further 42 days, she advised.

Sputnik V, licensed under an accelerated process before the end of clinical trials, has been given to doctors, soldiers, teachers and social workers in the first instance with a large-scale nationwide roll out due to begin this week. There are 21 days between the two Russian vaccine jabs.

“This really bothers me,” said Elena Kriven, a Moscow resident. “I’m unlikely to not be able to drink for 80 days and I reckon the stress on the body of giving up alcohol, especially during what is a festive period, would be worse than the [side effects of the] vaccine and its alleged benefits,” she said.

Kriven was referring to the main New Year public holiday. Many Russians will spend the first 10 days of 2021 relaxing at home or abroad, a period associated with higher alcohol use.

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15 minutes ago, Thai Spice said:

 

A very well articulated load of bollocks.

@Nightcrawler must be bored to death to have time for this stuff...

No more than anyone else I guess including yourself 

6am and you are right on it 😊

But if you are not interested in reading other people's opinions other than your own, may I suggest that you invest in a decent mirror. 

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11 hours ago, dcfc2007 said:

Why are you sharing Britain and the NHS. The NHS is a crumbling, bureaucratic shitpit full of diversity co-ordinators and some of the worst health outcomes in the developed world. 

 

Researchers have now completed the trial, known as the Adaptive COVID-19 Treatment Trial (ACTT-1). The study was funded by the National Institute of Allergy and Infectious Diseases (NIAID). The final report appeared in the New England Journal of Medicine on October 8, 2020.

Scientists randomly assigned 1,062 hospitalized COVID-19 patients to receive remdesivir or a placebo plus standard treatment. The patients received an intravenous infusion of remdesivir or placebo for up to 10 days.

The final results showed that the antiviral treatment was beneficial, consistent with the preliminary findings. Patients who received remdesivir were quicker to recover, which was defined as being medically stable enough to be discharged from the hospital. The median recovery time was 10 days with remdesivir compared to 15 days for the placebo group. Patients given remdesivir were more likely to have improved by day 15.

Remdesivir also improved mortality rates for those receiving supplemental oxygen (4% with remdesivir versus 13% with placebo at day 29 of treatment). All-cause mortality among all patients was 11% with remdesivir and 15% with placebo at day 29, but this difference between the treatment groups was not large enough to rule out chance. The preliminary findings hadn’t shown an effect on mortality.

The study also suggested that remdesivir treatment may prevent patients from progressing to more severe respiratory disease. Those treated with remdesivir were less likely to need high levels of respiratory support. Remdesivir appeared to most benefit patients who were receiving supplemental oxygen.

“Our findings show that remdesivir is a beneficial treatment for patients with COVID-19,” says study author Dr. John Beigel of NIAID. “It may also help to conserve scarce health care resources, such as ventilators, during this pandemic.”

https://www.nih.gov/news-events/nih-research-matters/final-report-confirms-remdesivir-benefits-covid-19#:~:text=By April%2C early results indicated,people hospitalized with COVID-19.

The patients received an intravenous infusion of remdesivir or placebo for up to 10 days.

So the patient is in hospital for at least 10 days.

Patients given remdesivir were more likely to have improved by day 15.

Or maybe they're in hospital for at least 15 days.

Remdesivir also improved mortality rates for those receiving supplemental oxygen (4% with remdesivir versus 13% with placebo at day 29 of treatment).

You need to be on supplemental oxygen to get any benefit?

The preliminary findings hadn’t shown an effect on mortality.

So what's the point, mortality is the Covid-19 effect I'm concerned about.

Remdesivir appeared to most benefit patients who were receiving supplemental oxygen.

Perhaps not needing supplemental oxygen in the first place would be a better alternative.

 

 

And the availability of remdesivir?????

 

 

 

 

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So much for the vaccine dreamers .....

Look at the new date !

 

Sanofi, GSK delay COVID-19 vaccine program

[11/12/2020] 14:16:00

Sanofi S.A. and GlaxoSmithKline plc announced on Friday that their COVID-19 vaccine program has been delayed due to insufficient immune response in the elderly population, so the jab is expected to be available by the last quarter of the next year.

"The results of the study are not as we hoped... Our aim now is to work closely with our partner Sanofi to develop this vaccine, with an improved antigen formulation, for it to make a meaningful contribution to preventing COVID-19," said President of GSK Vaccines, Roger Connor.

 

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31 minutes ago, Thai Spice said:

So much for the vaccine dreamers .....

Look at the new date !

 

Sanofi, GSK delay COVID-19 vaccine program

[11/12/2020] 14:16:00

Sanofi S.A. and GlaxoSmithKline plc announced on Friday that their COVID-19 vaccine program has been delayed due to insufficient immune response in the elderly population, so the jab is expected to be available by the last quarter of the next year.

"The results of the study are not as we hoped... Our aim now is to work closely with our partner Sanofi to develop this vaccine, with an improved antigen formulation, for it to make a meaningful contribution to preventing COVID-19," said President of GSK Vaccines, Roger Connor.

 

You do realise there's more vaccines than just these 2 ?

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36 minutes ago, Thai Spice said:

So much for the vaccine dreamers .....

Look at the new date !

 

Sanofi, GSK delay COVID-19 vaccine program

[11/12/2020] 14:16:00

Sanofi S.A. and GlaxoSmithKline plc announced on Friday that their COVID-19 vaccine program has been delayed due to insufficient immune response in the elderly population, so the jab is expected to be available by the last quarter of the next year.

"The results of the study are not as we hoped... Our aim now is to work closely with our partner Sanofi to develop this vaccine, with an improved antigen formulation, for it to make a meaningful contribution to preventing COVID-19," said President of GSK Vaccines, Roger Connor.

 

No big deal.

A protein based vaccine (Sanofi just reworked their flu vaccine).

University of Queensland's protein based vaccine also fell by the wayside today.

If I'm given a choice I'll go with either an mRNA or viral vector vaccine.

The immunologists I listen suggest that protein based vaccines may not give a very good T-cell response.

 

 

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